The Science Behind Our Novel Particles

Based on nanoparticle technology, our distinctive engineered platform has been used in a variety of biomedical applications. In cancer, NanoMedtrix material has been designed to target solid tumors such as: bladder, colorectal and neural tumors. The same nano-compounds are adjustable to provide valuable information on the disease process of a multitude of illnesses. What makes our approach unique is that target can be validated non-invasively and sequentially by microscopic and scanning methods without the need for further injections. This will lead to optimized prognostics.

 We have developed a platform technology with multiple biomedical applications.  One of the first and for most IND is it use in cancer.  The nanoparticles are able to deliver tumoricidal doses precisely.  A process that can be monitored noninvasively through contrast agent incorporation. We seek to attract pharmaceutical companies as potential strategic partner in this journey. 

  Ultimately, the patient will benefit from this technology. 

 Numerous drugs on the market have great potential to prevent various diseases, however the mode of delivery hinder and diminish the impact because of the delivery modality.  Our technology enable the drugs' efficacy and reduce off target liability.  This technology is born out of years of biomedical research in academic institutions and has received numerous awards from NIH and NSF. 

To enhance whole live animal studies, we have performed extensive characterization of our products and toxicology evaluation (with live cells and with adult and fetal laboratory animals).  Currently, we are focusing efforts on the preclinical products which allows validation and acceptance thought the scientific community. Our long term vision is to provide our products to physicians for clinical applications.

We provide an invaluable set of patent-pending multi-scale tools for research into early detection and treatment of diseases, with the goal of achieving greater cost effectiveness in medical care through early, accurate and rapid diagnosis followed by successful interventions.  Specifics of our science include sequential detection / quantification: 

 Mesenchymal stem cell labeled with MSN particles confocal microscopy fluorescent labeling 

  3-dimensional MRI "virtual cytoscopy" of a mouse bladder (gray) containing a tumor (red) labeled with NanoMedTrix MSN particles.  The particles improve the definition of the tumor boundaries and even show tumor growth within the bladder wall, important for tumor grading. 

 Echo of injected heart and 3D imaging.  Rapid image guiding information.  

 Targeted drug delivery of cancer drugs  to improve drug efficacy and reduce off-target liability.